个人简介

鞠峰， 湖北武汉人，特聘研究员，博士生导师。2008 年和 2011 年分别获得江汉大学和华南理工大学环境工程学士与硕士学位，2015 年获得香港大学工学博士学位。2015-2018年在瑞士联邦水科学和技术研究所（EAWAG）从事博士后研究。2018 年 9 月加入西湖大学，成立“环境微生物组与生物技术实验室”（EMBLab: www.ju-emblab.com），从事环境生物技术、微生物组学、合成生物学前沿交叉研究，曾获中国生态学学会“水云天微生物生态青年科技创新奖-特等奖”（2018）、香港科学会工程领域“青年科学家奖”（2016）、香港大学“杰出研究型研究生奖”（2015）等。目前，担任中国工程院院刊 Engineering 和 Engineering in Life Sciences 期刊编委，Frontiers in Microbiology 期刊副主编等学术职务；曾担任中国科学技术部、加拿大自然科学与工程研究委员会（NSERC）等机构评审专家。

学术成果

环境微生物组学研究环境中全部微生物及其遗传信息，其方法学基础与理论拓展应用是国际研究前沿和热点，关键科学问题包括（但不限于）：1）如何全面高效定量识别微生物群落? 2）群落如何构建并决定功能? 3）功能如何精准设计与靶向调控？西湖大学EMBLab开展环境工程学与微生物学交叉学科研究，研究兴趣包括：1）环境工程微生物组与合成生物学；2）抗生素耐药组及病原组监测与风险阻控；3）新污染物降解转化与环境健康效应；4）宏基因组学与微生物组学。

鞠峰博士近三年已主持或参与国家级或省部级科研项目 4 项；目前参编中英文专著 6 本，在Nature Communications、ISME Journal、Advanced Science、Environmental Science & Technology、Water Research等国际知名学术期刊发表SCI论文 60 余篇，引用 4200次。

代表论文

一、环境工程微生物组与群落构建理论

1. Wang H, Wang YB, Zhang GQ, Zhao Z, Ju F*. 2022. Temporal Dynamics and Performance Association of the Tetrasphaera-Enriched Microbiome for Enhanced Biological Phosphorus Removal, Engineering (accepted) (基于自上而下的设计策略构建强化生物除磷微生物组并验证了其用于回收污水中磷资源的应用潜力)

2. Gao H, Zhao Z, Zhang L, Ju F*. 2022. Cyanopeptides restriction and degradation co-mediate microbiota assembly during a freshwater cyanobacterial harmful algal bloom (CyanoHAB). Water Research. 220: 118674 (发现蓝藻多肽抑制与降解共同调控蓝藻水华爆发期间微生物组群落构建)

3. Zhang L, Yin W, Wang C, Zhang AJ, Zhang H, Ju F*. 2021. Untangling Microbiota Diversity and Assembly Patterns in the World's Largest Water Diversion Canal. Water Research. 117617 (首次揭示世界上规模最大调水工程渠道中微生物组群落构建与时空动态机制)

4. Ju F, Wang Y, Zhang T*. 2018. Bioreactor microbial ecosystems with differentiated methanogenic phenolbiodegradation and competitive metabolic pathways unraveled with genome-resolved metagenomics. Biotechnology for Biofuels 11(1), 135 (苯酚降解产甲烷微生物组代谢途径与互作机制)

5. Ju F, Lau, F, Zhang T*. 2017. Linking microbial community, environmental variables and methanogenesis in anaerobic biogas digesters of chemically enhanced primary treatment sludge. Environmental Science & Technology. 51 (7), 3982-3992 (厌氧消化产甲烷微生物组群落构建机制与效能关联)

6. Ju F, Zhang T*. 2015. Experimental design and bioinformatics analysis for the application of metagenomics in environmental sciences and biotechnology. Environmental Science & Technology. 49(21), 12628-1264 (环境科学与生物技术领域宏基因组学主题综述)

7. Ju F , Zhang T*. 2015. 16S rRNA gene high-throughput sequencing data mining of microbial diversity and interactions. Applied Microbiology and Biotechnology. 99(10): 4119-4129 (微生物组群落多样性与互作关系研究的扩增子数据分析综述)

8. Ju F, Zhang T*. 2015. Bacterial assembly and temporal dynamics in activated sludge of a full-scale municipal wastewater treatment plant. The ISME Journal. 9: 683-695 (揭示了城市污水处理厂活性污泥工艺细菌群落构建与时间动态机制)

9. Ju F, Xia Y, Guo F, Wang ZP, Zhang T*. 2014. Taxonomic relatedness shapes bacterial assembly in activated sludge of globally distributed wastewater treatment plants. Environmental Microbiology.16(8):2421-2432 (揭示了全球活性污泥污水处理厂细菌群落构建机制与空间分布格局)

二、抗生素耐药组及病原细菌监测与风险阻控

10. Zhang Z, Zhang G, Ju F*. 2022. Using Culture-Enriched Phenotypic Metagenomics for Targeted High-Throughput Monitoring of Clinically-Important Fraction of theβ-Lactam Resistome. Environmental Science & Technology. 56(16):11429-11439 (提出表型宏基因组学概念与技术框架，并首次应用于临床超广谱β-内酰胺抗生素耐药组的环境检测)

11. Yuan L, Wang Y, Zhang L, Alejandro P, Zhou J, Smets B, Bürgmann H, Ju F*.2021. Pathogenic and indigenous denitrifying bacteria are transcriptionally active and key multi-antibiotic resistant players in wastewater treatment plants. Environmental Science & Technology. 55(15): 10862-10874 (提出基因组水平的定量宏转录组学方法，发现反硝化细菌与病原细菌是城市污水处理厂多重耐药性活跃表达者)

12. Shuai M#, Zhang G#, Ju F*, Zheng J* et al. 2022. Human gut antibiotic resistome and progression of diabetes. Advanced Science. e2104965 (equal contribution) (发现肠道抗生素抗性组与糖尿病发展的关联)

13. Ju F, Beck K, Yin X, McArdell Christa, Singer H, Johnson D, Zhang T, Buergmann H*. 2019. Wastewater treatment plant resistomes are shaped by bacterial composition, genetic exchange and up-regulated expression in the effluent. The ISME Journal. 13 (2), 346:1 (提出了定量转录组学方法与技术框架，并首次用于探明城市污水处理厂抗性组的表达活性与关键驱动因素)

14. Ju F, Li B, Ma LP, Wang YB, Huang DP, Zhang T*. 2016. Antibiotic resistance genes and human bacterial pathogens: co-occurrence, removal, and enrichment in municipal sewage sludge digesters. Water Research. 91, 1-10 (揭示了厌氧消化过程对市政污泥人类病原细菌与抗生素抗性基因影响)

15. Li B#,·Ju F#,·Cai L,·Zhang T*. 2015. Profile and fate of bacterial pathogens in sewage treatment plants revealed by high-throughput metagenomic approach. Environmental Science & Technology.49 (17), 10492–10502 (equal contribution) (揭示了城市污水处理厂人类病原细菌的多样性与归趋)

三、新污染物降解转化和健康效应

16. Zhang Z, Peng H, Yang D, Zhang G, Zhang J, Ju F*. 2022. Polyvinyl chloride degradation by a bacterium isolated from the gut of insect larvae. Nature Communication. 13: 5360 (聚氯乙烯细菌降解机制解析新突破与首个解聚活性酶发现)

17. Yang XY#; Zhang L#, Chen Y*, Ju F* et al. 2022. Micro(nano)plastic Size and Concentration Co-Differentiate Nitrogen Transformation, Microbiota Dynamics, and Assembly Patterns in Constructed Wetlands. Water Research. 220: 118636 (equal contribution) (揭示了微纳塑料对人工湿地微生物组脱氮与群落构建机制影响)

18. He Y, Zhang Y, Ju F*. 2022. Metformin Contamination in Global Waters: Biotic and Abiotic Transformation, Byproduct Generation and Toxicity, and Evaluation as a Pharmaceutical Indicator. Environmental Science & Technology. 56, 19, 13528-13545  (综述评估了全球水环境二甲双胍污染物归趋、产物毒理与指示作用)

19. He Y , Jin H, Gao H, Zhang GQ, Ju F*. 2021. Prevalence, production, and ecotoxicity of chlorination-derived metformin byproducts in Chinese urban water systems. Science of the Total Environment. 151665 (首次揭示了二甲双胍氯化产物生态毒性及中国城镇水环境分布)

20. Zhang RS#, He YZ#, Yao LX#, Chen J, Zhu SH, Rao XX, Tang PY, You J, Hua GQ, Zhang L, Ju F*, Wu LF*. 2021. Metformin chlorination byproducts in drinking water exhibit marked toxicities of a potential health concern. Environment International. (146)106244  (发现了二甲双胍氯化副产物的显著毒性与潜在健康风险)

联系方式

　　电子邮箱：jufeng@westlake.edu.cn

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