时间：2019年10月22日（周四）下午 4:00-5:30
　　Time：October 22, 2019,4:00-5:30PM
　　地点：西湖大学云栖校区3号楼312
　　Venue:Meeting Room 312, Building 3, Yunqi Campus
　　主持人：生命科学学院PI 贾洁敏博士
　　Host：Dr. Jiemin Jia，PI ofSchool of Life Sciences, Westlake University
　　主讲嘉宾/Speaker:

　　Dr. Xiaofeng Jia

　　Professor of the Department of Neurosurgery, Orthopaedics, Anatomy Neurobiology, Director of the Translational Neuroengineering and Neuroscience Laboratory at the University of Maryland School of Medicine and the Adjunct  Associate Professor in the Department of Biomedical Engineering, Anesthesiology & Critical Care Medicine at Johns Hopkins University.
　　

主讲人简介/Biography:
　　Dr. Xiaofeng Jia received his medical degree from the Zhejiang University, a Ph.D. degree from Fudan University, and completed his residency training in surgery at the Huashan Hospital, Fudan University. He completed his postdoctoral training at the Department of Biomedical Engineering, Johns Hopkins University (2004-2007).
　　Xiaofeng Jia, MD, MS, PhD is the Professor of the Department of Neurosurgery, Orthopaedics, Anatomy Neurobiology, Director of the Translational Neuroengineering and Neuroscience Laboratory at the University of Maryland School of Medicine and the Adjunct  Associate Professor in the Department of Biomedical Engineering, Anesthesiology & Critical Care Medicine at Johns Hopkins University. He is a recipient of the Annual Research Awards from AAHS in 2008 (total 3 awarded nationally).
　　Dr. JIA is the Secretary and treasurer for the Research Section, and Scientific Review committee member of Society of Critical Care Medicine (SCCM), elected member (basic science) of the American Academy of Orthopaedic Surgeons (AAOS), elected full member of American Association for Hand Surgery (AAHS).
　　

讲座摘要/Abstract:
　　CA affects between 250,000 and 400,000 people annually and remains a major cause of death in the United States. Among the only 5-8% of CA patients who survive, neurological complications remain the leading cause of disability. Targeted temperature management (TTM, also called therapeutic hypothermia) significantly mitigates brain injury in animal models and enhances the survival and quality of life in clinical trials. Yet 5 out of every 6 treated patients continue to have poor outcomes. Moreover, the availability of bedside neurophysiologic testing has been largely limited for comatose CA survivors, particularly in patients who are treated with hypothermia. Dr. Jia will present early electrophysiological markers developed for monitoring the brain’s response to graded global hypoxic-ischemic brain injury, and the effect of temperature on neurological recovery in an asphyxia CA rat model, using electroencephalogram (EEG), somatosensory Evoked Potentials (SSEP), and high-resolution laser speckle contrast imaging (LSCI) technique to study the process of coma arousal after CA and to develop neurophysiological markers of recovery. These studies have the potential to discover clinically relevant and neurophysiologically validated electrical markers of arousal from coma after CA and explore the mechanism by which TTM enhances neurophysiological recovery.
　　

联系人/Contact：
　　生命科学学院
　　于文越 yuwenyue@westlake.edu.cn