时间：4月25日星期二16:00-17:30

Time：4:00-5:30 PM，Tuesday, April 25th，2023

主持人：西湖大学生命科学学院特聘研究员 陶亮

    Host：Dr. Liang Tao, PI of School of Life Sciences

    地点：云谷校区E9-109

    Venue：E9-109, Yungu Campus

主讲嘉宾/Speaker:

Tao Dong, Professor of School of Life Sciences, Southern University of Science and Technology

Dr. Tao Dong is a professor in the School of Life Sciences at the Southern University of Science and Technology. Dr. Dong obtained his BSc at Shandong University in 2003 and PhD at McMaster University in 2010. Funded by the prestigious Banting fellowship, he worked as a postdoctoral fellow at Harvard Medical School from 2011 to 2013. Prior to joining the SUSTech, he served as a full professor and two-term Canada Research Chair in Molecular Ecology of Waterborne Microbes at the University of Calgary. He has also worked as a special principal investigator and chaired the Department of Biochemistry and Molecular Biology at Shanghai Jiao Tong University. Dr. Dong’s research group is focused on understanding the molecular adaptation mechanisms that enable bacteria to survive in diverse natural and host environments, and the nature of bacterial interactions with other competing species. He has trained 10 postdoctoral fellows, 8 Ph.D. students, 7 MSc students, and over 20 undergraduate students.

讲座摘要/Abstract:

Microbes are invisible individually but they exist in astronomical numbers in the environment and in human bodies. They are not passive residents in the host but are actively interacting with each other and with the host cells. My lab focuses on the type VI protein secretion system (T6SS), which is an important interaction tool widely distributed in gram-negative bacteria. Analogous to a crossbow, the T6SS is a double-tubular structure anchored to the cell envelope and uses the instant contraction of a long sheath to power the ejection of an arrow-like tube and its associated toxins outward to penetrate neighbouring bacteria and host cells. I will discuss our work on the assembly mechanism, toxin functions, and engineering of the T6SS.   

联系人/Contact：

生命科学学院

于文越 yuwenyue@westlake.edu.cn