时间：2023年5月11日（周四）上午9:30~11:00

Time：9:30-11:00 AM, Thursday, May 11, 2023

地点：西湖大学云谷校区E10-201

Venue: E10-201, Yungu Campus

主持人：西湖大学工学院讲席教授曾安平

Host: Chair Professor Anping Zeng, School of Engineering

主讲人/Speaker：

Yajun Yan

Full Professor of University of Georgia

Professor Yajun Yan received his PhD in Chemical and Biological Engineering from the State University of New York at Buffalo in 2008. From 2008 to 2010, he worked as a postdoctoral researcher in Synthetic Biology and Metabolic Engineering at the University of California, Los Angeles. Since 2010, he has been a faculty member at the University of Georgia, where he was promoted to tenured Associate Professor in 2015 and to full Professor in 2019. Over the past 20 years, his research has focused mainly on Synthetic Biology and Metabolic Engineering. To date, Professor Yajun Yan has published around 110 journal articles and holds 17 patents in multiple countries including the US, China, and Canada.

报告题目/Title:

Metabolic Engineering Strategies towards Enhancing Synthetic Capability of Microbial Systems

讲座摘要/Abstract:

The use of microbial systems for synthetic purposes holds significant promise in the realm of green manufacturing. However, in order to fully unleash the potential of these systems, it is imperative to broaden the range of products that can be synthesized and improve the efficiency of biosynthesis. Achieving these goals necessitates concerted efforts in two areas: constructing synthetic pathways for compounds that are beyond the scope of natural hosts and developing overproducing strains. These efforts require the identification of new enzymes or the creation of novel enzymatic activities that can function in non-natural pathways, as well as the reprogramming of cellular metabolism and regulation to better support biosynthetic activities. In this seminar, we will present a selection of projects that showcase our understanding and experience in these fields, including: 1) repurposing enzymes to enable microbial synthesis of diverse specialty chemicals, and 2) establishing a modifiable carbon metabolism coordination system to promote carbon-efficient production.

讲座联系人/Contact:

科技合作部 sci-tech02@westlake.edu.cn