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For synthetic biology to realize its potential for compelling applications, it requires implementations beyond circuits driven by gene expression. Building proteins from the ground up through computational design offers the opportunity to implement synthetic biology design concepts at the molecular scale with unprecedented accuracy and complexity. In this Webinar from Cell Press and Westlake University, David Baker (University of Washington) and Brian Kuhlman (University of North Carolina), and Zibo Chen (Westlake University) discuss how advances in computational protein design can help inform and extend the scope of synthetic biology.

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