时间：2023年7月12日（周三）16:00-17:30 

Time：4:00-5:30 PM, Wednesday, July 12, 2023

地点：西湖大学云谷校区 行政楼A1一楼报告厅

Venue: Lecture Hall, A1, Yungu Campus

主持人：西湖大学生命科学学院讲席教授  于洪涛

Host: Dr. Hongtao Yu, Chair Professor, School of Life Sciences

Philip Beachy

The Ernest and Amelia Gallo Professor, 

Professor of Urology, Developmental Biology by courtesy, 

of Chemical and Systems Biology, Stanford University

Prof. Philip A. Beachy is a member of The American Academy of Arts and Sciences, and a member of National Academy of Sciences. He is currently the director of Siebel Investigator Program, Institute for Stem Cell Biology and Regenerative Medicine, and the Ernest and Amelia Gallo Professor at Stanford University School of Medicine. Dr. Beachy is a world-leading developmental biologist. His research interests mainly focus on functional characterization of Hedgehog proteins and other extracellular signals in morphogenesis and in injury repair and regeneration. He also studies the functional roles of various signaling molecules in stem cell physiology and how they can induce cancer stem cells. He discovered how Cyclopamine and Smoothened are related to Itraconazole, thus linking diverse fields of scientific research.

报告题目/Title:

Biology and Mechanism of Hedgehog Signaling in Regeneration and Malignancy

讲座摘要/Abstract:

Recent biochemical and structural studies reveal a central mechanistic role for lipids in Hedgehog signaling. These lipid-centric mechanisms will be discussed alongside emerging roles of Hedgehog pathway activity in stem cells or their cellular niches, with translational implications for tissue regeneration and malignancy.

讲座联系人/Contact:

科技合作部sci-tech02@westlake.edu.cn