时间：2023年10月25日（周三）上午10:00~11:30

Time：10:00-11:30 AM, Wednesday, October 25, 2023

地点：西湖大学云谷校区E9-109

Venue: E9-109, Yungu Campus

主持人：西湖大学生命科学学院 讲席教授 于洪涛

Host: Dr. Hongtao Yu, Chair Professor, School of Life Sciences

主讲人/Speaker：

Jing W. Wang

Professor，

School of Biological Sciences

University of California, San Diego

报告题目/Title:

Circuit Topology and the Hierarchy of Needs

讲座摘要/Abstract:

Animals typically display one behavior at a time, with protocols governing the switch from one behavior to another at the appropriate moment. Similarly, large-scale electronic systems have operational protocols that are shaped by circuit topology. Our study aimed to investigate the protocol and circuit topology of feeding and courtship behaviors in Drosophila. We found feeding is initially prioritized in starved males, but the intake of protein-rich food triggers a swift protocol change, prioritizing courtship within minutes. This shift is mediated by a gut-derived neuropeptide, Diuretic hormone 31 (Dh31). Amino acids in food activate Dh31+ enteroendocrine cells, leading to elevated circulating Dh31 levels that subsequently excite specific brain neurons, with one population inhibiting feeding and the other promoting courtship. Our findings illustrate a flexible circuit topology that determines behavioral protocols.

讲座联系人/Contact:

科技合作部Sci-tech02@westlake.edu.cn